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Suppressyn localization and dynamic expression patterns in primary human tissues support a physiologic role in human placentation

We previously identified suppressyn (SUPYN), a placental protein that negatively regulates the cell fusion essential for trophoblast syncytialization via binding to the trophoblast receptor for syncytin-1, ASCT2, and hypothesized that SUPYN may thereby regulate cell-cell fusion in the placenta. Here...

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Detalles Bibliográficos
Autores principales: Sugimoto, Jun, Schust, Danny J., Kinjo, Tadatsugu, Aoki, Yoichi, Jinno, Yoshihiro, Kudo, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925194/
https://www.ncbi.nlm.nih.gov/pubmed/31862915
http://dx.doi.org/10.1038/s41598-019-55933-x