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Deletion of the serine protease CAP2/Tmprss4 leads to dysregulated renal water handling upon dietary potassium depletion

The kidney needs to adapt daily to variable dietary K(+) contents via various mechanisms including diuretic, acid-base and hormonal changes that are still not fully understood. In this study, we demonstrate that following a K(+)-deficient diet in wildtype mice, the serine protease CAP2/Tmprss4 is up...

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Detalles Bibliográficos
Autores principales: Keppner, Anna, Maric, Darko, Sergi, Chloé, Ansermet, Camille, De Bellis, Damien, Kratschmar, Denise V., Canonica, Jérémie, Klusonova, Petra, Fenton, Robert A., Odermatt, Alex, Crambert, Gilles, Hoogewijs, David, Hummler, Edith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925205/
https://www.ncbi.nlm.nih.gov/pubmed/31863073
http://dx.doi.org/10.1038/s41598-019-55995-x