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Deletion of the serine protease CAP2/Tmprss4 leads to dysregulated renal water handling upon dietary potassium depletion
The kidney needs to adapt daily to variable dietary K(+) contents via various mechanisms including diuretic, acid-base and hormonal changes that are still not fully understood. In this study, we demonstrate that following a K(+)-deficient diet in wildtype mice, the serine protease CAP2/Tmprss4 is up...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925205/ https://www.ncbi.nlm.nih.gov/pubmed/31863073 http://dx.doi.org/10.1038/s41598-019-55995-x |