Cargando…

Dual microglia effects on blood brain barrier permeability induced by systemic inflammation

Microglia survey brain parenchyma, responding to injury and infections. Microglia also respond to systemic disease, but the role of blood–brain barrier (BBB) integrity in this process remains unclear. Using simultaneous in vivo imaging, we demonstrated that systemic inflammation induces CCR5-depende...

Descripción completa

Detalles Bibliográficos
Autores principales: Haruwaka, Koichiro, Ikegami, Ako, Tachibana, Yoshihisa, Ohno, Nobuhiko, Konishi, Hiroyuki, Hashimoto, Akari, Matsumoto, Mami, Kato, Daisuke, Ono, Riho, Kiyama, Hiroshi, Moorhouse, Andrew J., Nabekura, Junichi, Wake, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925219/
https://www.ncbi.nlm.nih.gov/pubmed/31862977
http://dx.doi.org/10.1038/s41467-019-13812-z