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Dual microglia effects on blood brain barrier permeability induced by systemic inflammation
Microglia survey brain parenchyma, responding to injury and infections. Microglia also respond to systemic disease, but the role of blood–brain barrier (BBB) integrity in this process remains unclear. Using simultaneous in vivo imaging, we demonstrated that systemic inflammation induces CCR5-depende...
Autores principales: | Haruwaka, Koichiro, Ikegami, Ako, Tachibana, Yoshihisa, Ohno, Nobuhiko, Konishi, Hiroyuki, Hashimoto, Akari, Matsumoto, Mami, Kato, Daisuke, Ono, Riho, Kiyama, Hiroshi, Moorhouse, Andrew J., Nabekura, Junichi, Wake, Hiroaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925219/ https://www.ncbi.nlm.nih.gov/pubmed/31862977 http://dx.doi.org/10.1038/s41467-019-13812-z |
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