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Descending motor circuitry required for NT-3 mediated locomotor recovery after spinal cord injury in mice

Locomotor function, mediated by lumbar neural circuitry, is modulated by descending spinal pathways. Spinal cord injury (SCI) interrupts descending projections and denervates lumbar motor neurons (MNs). We previously reported that retrogradely transported neurotrophin-3 (NT-3) to lumbar MNs attenuat...

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Detalles Bibliográficos
Autores principales: Han, Qi, Ordaz, Josue D., Liu, Nai-Kui, Richardson, Zoe, Wu, Wei, Xia, Yongzhi, Qu, Wenrui, Wang, Ying, Dai, Heqiao, Zhang, Yi Ping, Shields, Christopher B., Smith, George M., Xu, Xiao-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925225/
https://www.ncbi.nlm.nih.gov/pubmed/31862889
http://dx.doi.org/10.1038/s41467-019-13854-3