Cargando…
Descending motor circuitry required for NT-3 mediated locomotor recovery after spinal cord injury in mice
Locomotor function, mediated by lumbar neural circuitry, is modulated by descending spinal pathways. Spinal cord injury (SCI) interrupts descending projections and denervates lumbar motor neurons (MNs). We previously reported that retrogradely transported neurotrophin-3 (NT-3) to lumbar MNs attenuat...
Autores principales: | Han, Qi, Ordaz, Josue D., Liu, Nai-Kui, Richardson, Zoe, Wu, Wei, Xia, Yongzhi, Qu, Wenrui, Wang, Ying, Dai, Heqiao, Zhang, Yi Ping, Shields, Christopher B., Smith, George M., Xu, Xiao-Ming |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925225/ https://www.ncbi.nlm.nih.gov/pubmed/31862889 http://dx.doi.org/10.1038/s41467-019-13854-3 |
Ejemplares similares
-
Remodeling of lumbar motor circuitry remote to a thoracic spinal cord injury promotes locomotor recovery
por: Wang, Ying, et al.
Publicado: (2018) -
Molecular and cellular development of spinal cord locomotor circuitry
por: Lu, Daniel C., et al.
Publicado: (2015) -
Transhemispheric cortex remodeling promotes forelimb recovery after spinal cord injury
por: Wu, Wei, et al.
Publicado: (2022) -
Maturation of the Locomotor Circuitry in Children With Cerebral Palsy
por: Cappellini, Germana, et al.
Publicado: (2020) -
Neurotrophin-3-mediated locomotor recovery: a novel therapeutic strategy targeting lumbar neural circuitry after spinal cord injury
por: Han, Qi, et al.
Publicado: (2020)