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Computational discovery of hidden breaks in 28S ribosomal RNAs across eukaryotes and consequences for RNA Integrity Numbers

In some eukaryotes, a ‘hidden break’ has been described in which the 28S ribosomal RNA molecule is cleaved into two subparts. The break is common in protostome animals (arthropods, molluscs, annelids etc.), but a break has also been reported in some vertebrates and non-metazoan eukaryotes. We presen...

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Detalles Bibliográficos
Autores principales: Natsidis, Paschalis, Schiffer, Philipp H., Salvador-Martínez, Irepan, Telford, Maximilian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925239/
https://www.ncbi.nlm.nih.gov/pubmed/31863008
http://dx.doi.org/10.1038/s41598-019-55573-1