Butyrate inhibits visceral allodynia and colonic hyperpermeability in rat models of irritable bowel syndrome

Lipopolysaccharide (LPS) or repeated water avoidance stress (WAS) induces visceral allodynia and gut hyperpermeability via corticotropin-releasing factor (CRF) and proinflammatory cytokines, which is a rat irritable bowel syndrome (IBS) model. As butyrate is known to suppress the release of proinfla...

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Detalles Bibliográficos
Autores principales: Nozu, Tsukasa, Miyagishi, Saori, Nozu, Rintaro, Takakusaki, Kaoru, Okumura, Toshikatsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925246/
https://www.ncbi.nlm.nih.gov/pubmed/31862976
http://dx.doi.org/10.1038/s41598-019-56132-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925246/
https://www.ncbi.nlm.nih.gov/pubmed/31862976
http://dx.doi.org/10.1038/s41598-019-56132-4

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