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Butyrate inhibits visceral allodynia and colonic hyperpermeability in rat models of irritable bowel syndrome
Lipopolysaccharide (LPS) or repeated water avoidance stress (WAS) induces visceral allodynia and gut hyperpermeability via corticotropin-releasing factor (CRF) and proinflammatory cytokines, which is a rat irritable bowel syndrome (IBS) model. As butyrate is known to suppress the release of proinfla...
Autores principales: | Nozu, Tsukasa, Miyagishi, Saori, Nozu, Rintaro, Takakusaki, Kaoru, Okumura, Toshikatsu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925246/ https://www.ncbi.nlm.nih.gov/pubmed/31862976 http://dx.doi.org/10.1038/s41598-019-56132-4 |
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