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TIPRL potentiates survival of lung cancer by inducing autophagy through the eIF2α-ATF4 pathway

Autophagy, an intracellular system of degrading damaged organelles and misfolded proteins, is essential for cancer cell survival. Despite the progress made towards understanding the mechanism, identification of novel autophagy regulators presents a major obstacle in developing anticancer therapies....

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Detalles Bibliográficos
Autores principales: Jeon, Su-Jin, Ahn, Jun-Ho, Halder, Debasish, Cho, Hyun-Soo, Lim, Jung-Hwa, Jun, Soo Young, Lee, Jeong-Ju, Yoon, Ji-Yong, Choi, Min-Hyuk, Jung, Cho-Rok, Kim, Jin-Man, Kim, Nam-Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925247/
https://www.ncbi.nlm.nih.gov/pubmed/31862913
http://dx.doi.org/10.1038/s41419-019-2190-0