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TIPRL potentiates survival of lung cancer by inducing autophagy through the eIF2α-ATF4 pathway
Autophagy, an intracellular system of degrading damaged organelles and misfolded proteins, is essential for cancer cell survival. Despite the progress made towards understanding the mechanism, identification of novel autophagy regulators presents a major obstacle in developing anticancer therapies....
Autores principales: | Jeon, Su-Jin, Ahn, Jun-Ho, Halder, Debasish, Cho, Hyun-Soo, Lim, Jung-Hwa, Jun, Soo Young, Lee, Jeong-Ju, Yoon, Ji-Yong, Choi, Min-Hyuk, Jung, Cho-Rok, Kim, Jin-Man, Kim, Nam-Soon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925247/ https://www.ncbi.nlm.nih.gov/pubmed/31862913 http://dx.doi.org/10.1038/s41419-019-2190-0 |
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