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An experiment-informed signal transduction model for the role of the Staphylococcus aureus MecR1 protein in β-lactam resistance

The treatment of hospital- and community-associated infections by methicillin-resistant Staphylococcus aureus (MRSA) is a perpetual challenge. This Gram-positive bacterium is resistant specifically to β-lactam antibiotics, and generally to many other antibacterial agents. Its resistance mechanisms t...

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Detalles Bibliográficos
Autores principales: Belluzo, Bruno S., Abriata, Luciano A., Giannini, Estefanía, Mihovilcevic, Damila, Dal Peraro, Matteo, Llarrull, Leticia I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925264/
https://www.ncbi.nlm.nih.gov/pubmed/31862951
http://dx.doi.org/10.1038/s41598-019-55923-z