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Intestinal Neurod1 expression impairs paneth cell differentiation and promotes enteroendocrine lineage specification

Transcription factor Neurod1 is required for enteroendocrine progenitor differentiation and maturation. Several earlier studies indicated that ectopic expression of Neurod1 converted non- neuronal cells into neurons. However, the functional consequence of ectopic Neurod1 expression has not been exam...

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Detalles Bibliográficos
Autores principales: Li, Hui Joyce, Ray, Subir K., Pan, Ning, Haigh, Jody, Fritzsch, Bernd, Leiter, Andrew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925293/
https://www.ncbi.nlm.nih.gov/pubmed/31862906
http://dx.doi.org/10.1038/s41598-019-55292-7