Polyanions provide selective control of APC/C interactions with the activator subunit

Transient interactions between the anaphase-promoting complex/cyclosome (APC/C) and its activator subunit Cdc20 or Cdh1 generate oscillations in ubiquitylation activity necessary to maintain the order of cell cycle events. Activator binds the APC/C with high affinity and exhibits negligible dissocia...

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Detalles Bibliográficos
Autores principales: Mizrak, Arda, Morgan, David O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925294/
https://www.ncbi.nlm.nih.gov/pubmed/31862931
http://dx.doi.org/10.1038/s41467-019-13864-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925294/
https://www.ncbi.nlm.nih.gov/pubmed/31862931
http://dx.doi.org/10.1038/s41467-019-13864-1

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