Dusp8 affects hippocampal size and behavior in mice and humans

Dual-specificity phosphatase 8 (Dusp8) acts as physiological inhibitor for the MAPKs Jnk, Erk and p38 which are involved in regulating multiple CNS processes. While Dusp8 expression levels are high in limbic areas such as the hippocampus, the functional role of Dusp8 in hippocampus morphology, MAPK-...

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Detalles Bibliográficos
Autores principales: Baumann, Peter, Schriever, Sonja C., Kullmann, Stephanie, Zimprich, Annemarie, Feuchtinger, Annette, Amarie, Oana, Peter, Andreas, Walch, Axel, Gailus-Durner, Valerie, Fuchs, Helmut, Hrabě de Angelis, Martin, Wurst, Wolfgang, Tschöp, Matthias H., Heni, Martin, Hölter, Sabine M., Pfluger, Paul T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925303/
https://www.ncbi.nlm.nih.gov/pubmed/31862894
http://dx.doi.org/10.1038/s41598-019-55527-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925303/
https://www.ncbi.nlm.nih.gov/pubmed/31862894
http://dx.doi.org/10.1038/s41598-019-55527-7

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