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Is fibrodysplasia ossificans progressiva an interleukin-1 driven auto-inflammatory syndrome?
BACKGROUND: Fibrodysplasia ossificans progressiva (FOP) is the most catastrophic form of heterotopic ossification, due to ongoing intracellular signaling through the bone morphogenic protein pathway. The paroxysmal appearance of inflammatory lumps and elevated inflammatory markers during flares, sug...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925442/ https://www.ncbi.nlm.nih.gov/pubmed/31864380 http://dx.doi.org/10.1186/s12969-019-0386-6 |