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Is fibrodysplasia ossificans progressiva an interleukin-1 driven auto-inflammatory syndrome?

BACKGROUND: Fibrodysplasia ossificans progressiva (FOP) is the most catastrophic form of heterotopic ossification, due to ongoing intracellular signaling through the bone morphogenic protein pathway. The paroxysmal appearance of inflammatory lumps and elevated inflammatory markers during flares, sug...

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Detalles Bibliográficos
Autores principales: Haviv, Ruby, Moshe, Veronica, De Benedetti, Fabrizio, Prencipe, Giusi, Rabinowicz, Noa, Uziel, Yosef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925442/
https://www.ncbi.nlm.nih.gov/pubmed/31864380
http://dx.doi.org/10.1186/s12969-019-0386-6