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Blocking the PD-1/PD-L1 axis enhanced cisplatin chemotherapy in osteosarcoma in vitro and in vivo

BACKGROUND: The blocking of the programmed cell death protein (PD-1)/programmed death-ligand 1 (PD-L1) axis has been found to have an anticancer activity against various types of cancer by enhancing T cell immunity, while there are no studies linking the PD-1/PD-L1 axis to chemotherapy drugs in oste...

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Detalles Bibliográficos
Autores principales: Liu, Xiaoqiang, He, Shaoya, Wu, Huaming, Xie, Hui, Zhang, Tao, Deng, Zhongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925464/
https://www.ncbi.nlm.nih.gov/pubmed/31864288
http://dx.doi.org/10.1186/s12199-019-0835-3