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Melatonin promotes the BMP9-induced osteogenic differentiation of mesenchymal stem cells by activating the AMPK/β-catenin signalling pathway

BACKGROUND: Mesenchymal stem cells (MSCs) play a crucial role in maintaining the dynamic balance of bone metabolism. Melatonin may have a regulatory effect on bone metabolism by regulating the lineage commitment and differentiation signalling pathways of MSCs. Among the BMP families, the osteogenesi...

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Detalles Bibliográficos
Autores principales: Jiang, Tianyuan, Xia, Chao, Chen, Xiaoting, Hu, Yan, Wang, Yan, Wu, Jin, Chen, Shuyan, Gao, Yanhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925474/
https://www.ncbi.nlm.nih.gov/pubmed/31864412
http://dx.doi.org/10.1186/s13287-019-1511-7