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Lupus serum IgG induces microglia activation through Fc fragment dependent way and modulated by B-cell activating factor

BACKGROUND: Neuropsychiatric manifestations are frequent in patients with systemic lupus erythematosus (SLE), yet the etiology and pathogenesis of brain damage in SLE remains unclear. Because the production of autoantibodies, formation and deposition of immunocomplexes are major serological characte...

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Detalles Bibliográficos
Autores principales: Yang, Chunshu, Hou, Xiaoyu, Feng, Qianhui, Li, Yingzhuo, Wang, Xuejiao, Qin, Ling, Yang, Pingting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925475/
https://www.ncbi.nlm.nih.gov/pubmed/31864410
http://dx.doi.org/10.1186/s12967-019-02175-0