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Lupus serum IgG induces microglia activation through Fc fragment dependent way and modulated by B-cell activating factor
BACKGROUND: Neuropsychiatric manifestations are frequent in patients with systemic lupus erythematosus (SLE), yet the etiology and pathogenesis of brain damage in SLE remains unclear. Because the production of autoantibodies, formation and deposition of immunocomplexes are major serological characte...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925475/ https://www.ncbi.nlm.nih.gov/pubmed/31864410 http://dx.doi.org/10.1186/s12967-019-02175-0 |