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Inhibitor 1 of Protein Phosphatase 1 Regulates Ca(2+)/Calmodulin-Dependent Protein Kinase II to Alleviate Oxidative Stress in Hypoxia-Reoxygenation Injury of Cardiomyocytes

Ca(2+)/calmodulin-dependent protein kinase II (CaMKII), regulated by inhibitor 1 of protein phosphatase 1 (I1PP1), is vital for maintaining cardiovascular homeostasis. However, the role and mechanism of I1PP1 against hypoxia-reoxygenation (H/R) injury in cardiomyocytes remain a question. In our stud...

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Detalles Bibliográficos
Autores principales: Luo, Huiqin, Song, Shu, Chen, Yun, Xu, Mengting, Sun, Linlin, Meng, Guoliang, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925801/
https://www.ncbi.nlm.nih.gov/pubmed/31885777
http://dx.doi.org/10.1155/2019/2193019