Clusterin Silencing in Prostate Cancer Induces Matrix Metalloproteinases by an NF-κB-Dependent Mechanism

Clusterin (CLU) is a stress-activated glycoprotein, whose expression is altered both in inflammation and cancer. Previously, we showed that abrogation of CLU expression in cancer-prone mice (TRAMP) results in the enhancement of tumor spreading and homing, concomitant with an enhanced expression of N...

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Detalles Bibliográficos
Autores principales: Bonacini, Martina, Negri, Aide, Davalli, Pierpaola, Naponelli, Valeria, Ramazzina, Ileana, Lenzi, Chiara, Bettuzzi, Saverio, Rizzi, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925831/
https://www.ncbi.nlm.nih.gov/pubmed/31885575
http://dx.doi.org/10.1155/2019/4081624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925831/
https://www.ncbi.nlm.nih.gov/pubmed/31885575
http://dx.doi.org/10.1155/2019/4081624

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