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Clusterin Silencing in Prostate Cancer Induces Matrix Metalloproteinases by an NF-κB-Dependent Mechanism
Clusterin (CLU) is a stress-activated glycoprotein, whose expression is altered both in inflammation and cancer. Previously, we showed that abrogation of CLU expression in cancer-prone mice (TRAMP) results in the enhancement of tumor spreading and homing, concomitant with an enhanced expression of N...
Autores principales: | Bonacini, Martina, Negri, Aide, Davalli, Pierpaola, Naponelli, Valeria, Ramazzina, Ileana, Lenzi, Chiara, Bettuzzi, Saverio, Rizzi, Federica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925831/ https://www.ncbi.nlm.nih.gov/pubmed/31885575 http://dx.doi.org/10.1155/2019/4081624 |
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