POLE mutations improve the prognosis of endometrial cancer via regulating cellular metabolism through AMF/AMFR signal transduction

BACKGROUND: The morbidity and mortality of endometrial tumors, a common type of malignant cancer in women, have increased in recent years. POLE encodes the DNA polymerase ε, which is responsible for the leading strand DNA replication. Somatic mutations of POLE have been acknowledged in numerous canc...

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Detalles Bibliográficos
Autores principales: Li, Yiran, Bian, Yiding, Wang, Kai, Wan, Xiao-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925869/
https://www.ncbi.nlm.nih.gov/pubmed/31864301
http://dx.doi.org/10.1186/s12881-019-0936-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925869/
https://www.ncbi.nlm.nih.gov/pubmed/31864301
http://dx.doi.org/10.1186/s12881-019-0936-2

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