ALCAT1 Overexpression Affects Supercomplex Formation and Increases ROS in Respiring Mitochondria

Cardiolipin (CL) is a multifunctional dimeric phospholipid that physically interacts with electron transport chain complexes I, III, and IV, and ATP synthase (complex V). The enzyme ALCAT1 catalyzes the conversion of cardiolipin by incorporating polyunsaturated fatty acids into cardiolipin. The resu...

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Detalles Bibliográficos
Autores principales: Rieger, Bettina, Krajčová, Adéla, Duwe, Patrick, Busch, Karin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925921/
https://www.ncbi.nlm.nih.gov/pubmed/31885824
http://dx.doi.org/10.1155/2019/9186469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925921/
https://www.ncbi.nlm.nih.gov/pubmed/31885824
http://dx.doi.org/10.1155/2019/9186469

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