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Structural and Functional Analysis of human lung cancer risk associated hOGG1 variant Ser326Cys in DNA repair gene by molecular dynamics simulation
Oxidative damaged DNA base lesions are repaired through human 8-oxoguanine DNA glycosylase gene (hOGG1) mediated pathways. A recent report based on the meta-analysis has suggested that the DNA Repair Gene hOGG1 variant Ser326Cys [3p26.2; allele S/C in nucleotide position αHelix2 Ser⇒Cys326] was asso...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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KeAi Publishing
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926185/ https://www.ncbi.nlm.nih.gov/pubmed/31891019 http://dx.doi.org/10.1016/j.ncrna.2019.10.002 |