Hydrophobically Modified let-7b miRNA Enhances Biodistribution to NSCLC and Downregulates HMGA2 In Vivo

MicroRNAs (miRNAs) have increasingly been shown to be involved in human cancer, and interest has grown about the potential use of miRNAs for cancer therapy. miRNA levels are known to be altered in cancer cells, including in non-small cell lung cancer (NSCLC), a subtype of lung cancer that is the mos...

Descripción completa

Detalles Bibliográficos
Autores principales: Segal, Meirav, Biscans, Annabelle, Gilles, Maud-Emmanuelle, Anastasiadou, Eleni, De Luca, Roberto, Lim, Jihoon, Khvorova, Anastasia, Slack, Frank J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926262/
https://www.ncbi.nlm.nih.gov/pubmed/31855835
http://dx.doi.org/10.1016/j.omtn.2019.11.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926262/
https://www.ncbi.nlm.nih.gov/pubmed/31855835
http://dx.doi.org/10.1016/j.omtn.2019.11.008

Ejemplares similares