Autocrine BMP4 Signaling Enhances Tumor Aggressiveness via Promoting Wnt/β-Catenin Signaling in IDH1-mutant Gliomas

The isocitrate dehydrogenase (IDH1/2) mutations are frequent genetic abnormalities in the majority of WHO grade II/III glioma and secondary GBM. IDH1-mutated (IDH1(Mut)) glioma exhibits distinctive patterns in cancer biology and metabolism. In the present study, we showed that bone morphogenetic pro...

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Detalles Bibliográficos
Autores principales: Zhou, Yiqiang, Liu, Yang, Zhang, Junwen, Yu, Di, Li, Aiguo, Song, Hua, Zhang, Wei, Davis, Dionne, Gilbert, Mark R., Liu, Fusheng, Yang, Chunzhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926316/
https://www.ncbi.nlm.nih.gov/pubmed/31865175
http://dx.doi.org/10.1016/j.tranon.2019.10.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926316/
https://www.ncbi.nlm.nih.gov/pubmed/31865175
http://dx.doi.org/10.1016/j.tranon.2019.10.019

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