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Isolating peripheral effects of endogenous opioids in modulating exertional breathlessness in people with moderate or severe COPD: a randomised controlled trial

QUESTION ADDRESSED BY THE STUDY: Endogenous opioids (endorphins) have been reported to modulate exercise-induced breathlessness, but the relative contribution of peripheral opioid receptors has not been tested. MATERIALS, PARTICIPANTS AND METHODS: This was a double-blind, randomised, three-arm, cros...

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Detalles Bibliográficos
Autores principales: Currow, David C., Hunt, Toby, Louw, Sandra, Eckert, Danny, Allcroft, Peter, To, Tim H.M., Greene, Aine, Krajnik, Malgorzata, Mahler, Don, Ekström, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926367/
https://www.ncbi.nlm.nih.gov/pubmed/31886161
http://dx.doi.org/10.1183/23120541.00153-2019