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EPAC1 and EPAC2 promote nociceptor hyperactivity associated with chronic pain after spinal cord injury
Chronic pain following spinal cord injury (SCI) is associated with electrical hyperactivity (spontaneous and evoked) in primary nociceptors. Cyclic adenosine monophosphate (cAMP) signaling is an important contributor to nociceptor excitability, and knockdown of the cAMP effector, exchange protein ac...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926371/ https://www.ncbi.nlm.nih.gov/pubmed/31890991 http://dx.doi.org/10.1016/j.ynpai.2019.100040 |