EPAC1 and EPAC2 promote nociceptor hyperactivity associated with chronic pain after spinal cord injury

Chronic pain following spinal cord injury (SCI) is associated with electrical hyperactivity (spontaneous and evoked) in primary nociceptors. Cyclic adenosine monophosphate (cAMP) signaling is an important contributor to nociceptor excitability, and knockdown of the cAMP effector, exchange protein ac...

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Detalles Bibliográficos
Autores principales: Berkey, Samantha C., Herrera, Juan J., Odem, Max A., Rahman, Simran, Cheruvu, Sai S., Cheng, Xiaodong, Walters, Edgar T., Dessauer, Carmen W., Bavencoffe, Alexis G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926371/
https://www.ncbi.nlm.nih.gov/pubmed/31890991
http://dx.doi.org/10.1016/j.ynpai.2019.100040

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