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N-Glycosylation of mollusk hemocyanins contributes to their structural stability and immunomodulatory properties in mammals

Hemocyanins are widely used as carriers, adjuvants, and nonspecific immunostimulants in cancer because they promote Th1 immunity in mammals. Hemocyanins also interact with glycan-recognizing innate immune receptors on antigen-presenting cells, such as the C-type lectin immune receptors mannose recep...

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Detalles Bibliográficos
Autores principales: Salazar, Michelle L., Jiménez, José M., Villar, Javiera, Rivera, Maira, Báez, Mauricio, Manubens, Augusto, Becker, María Inés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926458/
https://www.ncbi.nlm.nih.gov/pubmed/31719148
http://dx.doi.org/10.1074/jbc.RA119.009525