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Origin of Lactose Fermentation in Kluyveromyces lactis by Interspecies Transfer of a Neo-functionalized Gene Cluster during Domestication

Humans have used yeasts to make cheese and kefir for millennia, but the ability to ferment the milk sugar lactose is found in only a few yeast species, of which the foremost is Kluyveromyces lactis [1]. Two genes, LAC12 (lactose permease) and LAC4 (lactase), are sufficient for lactose uptake and hyd...

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Detalles Bibliográficos
Autores principales: Varela, Javier A., Puricelli, Martina, Ortiz-Merino, Raúl A., Giacomobono, Romina, Braun-Galleani, Stephanie, Wolfe, Kenneth H., Morrissey, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926475/
https://www.ncbi.nlm.nih.gov/pubmed/31813610
http://dx.doi.org/10.1016/j.cub.2019.10.044