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In Vitro Assessment of the Efficacy of a Macrocyclic Chelator in Reversing Methylmercury Toxicity

Methylmercury (MeHg) is a highly neurotoxic compound to which human populations are exposed via fish consumption. Once in cells, MeHg actively binds thiols and selenols, interfering with the activity of redox enzymes such as thioredoxin (Trx) and the selenoenzyme thioredoxin reductase (TrxR) which i...

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Detalles Bibliográficos
Autores principales: Nobre, Paula, Cabral, Maria de Fátima, Costa, Judite, Castro-Caldas, Margarida, Carvalho, Cristina, Branco, Vasco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926914/
https://www.ncbi.nlm.nih.gov/pubmed/31801208
http://dx.doi.org/10.3390/ijerph16234817