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In Vitro Assessment of the Efficacy of a Macrocyclic Chelator in Reversing Methylmercury Toxicity
Methylmercury (MeHg) is a highly neurotoxic compound to which human populations are exposed via fish consumption. Once in cells, MeHg actively binds thiols and selenols, interfering with the activity of redox enzymes such as thioredoxin (Trx) and the selenoenzyme thioredoxin reductase (TrxR) which i...
Autores principales: | Nobre, Paula, Cabral, Maria de Fátima, Costa, Judite, Castro-Caldas, Margarida, Carvalho, Cristina, Branco, Vasco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926914/ https://www.ncbi.nlm.nih.gov/pubmed/31801208 http://dx.doi.org/10.3390/ijerph16234817 |
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