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A Combination of an Antimitotic and a Bromodomain 4 Inhibitor Synergistically Inhibits the Metastatic MDA-MB-231 Breast Cancer Cell Line

Current chemotherapeutic agents have many side effects and are toxic to normal cells, providing impetus to identify agents that can effectively eliminate tumorigenic cells without damaging healthy cells. The aim of this study was to examine whether combining a novel BRD4 inhibitor, ITH-47, with the...

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Detalles Bibliográficos
Autores principales: Mqoco, Thandi, Stander, André, Engelbrecht, Anna-Mart, Joubert, Anna M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927020/
https://www.ncbi.nlm.nih.gov/pubmed/31886177
http://dx.doi.org/10.1155/2019/1850462