HPOAnnotator: improving large-scale prediction of HPO annotations by low-rank approximation with HPO semantic similarities and multiple PPI networks

BACKGROUND: As a standardized vocabulary of phenotypic abnormalities associated with human diseases, the Human Phenotype Ontology (HPO) has been widely used by researchers to annotate phenotypes of genes/proteins. For saving the cost and time spent on experiments, many computational approaches have...

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Detalles Bibliográficos
Autores principales: Gao, Junning, Liu, Lizhi, Yao, Shuwei, Huang, Xiaodi, Mamitsuka, Hiroshi, Zhu, Shanfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927106/
https://www.ncbi.nlm.nih.gov/pubmed/31865916
http://dx.doi.org/10.1186/s12920-019-0625-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927106/
https://www.ncbi.nlm.nih.gov/pubmed/31865916
http://dx.doi.org/10.1186/s12920-019-0625-1

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