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The essentiality landscape of cell cycle related genes in human pluripotent and cancer cells

BACKGROUND: Cell cycle regulation is a complex system consisting of growth-promoting and growth-restricting mechanisms, whose coordinated activity is vital for proper division and propagation. Alterations in this regulation may lead to uncontrolled proliferation and genomic instability, triggering c...

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Detalles Bibliográficos
Autores principales: Viner-Breuer, Ruth, Yilmaz, Atilgan, Benvenisty, Nissim, Goldberg, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927170/
https://www.ncbi.nlm.nih.gov/pubmed/31889988
http://dx.doi.org/10.1186/s13008-019-0058-4