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The essentiality landscape of cell cycle related genes in human pluripotent and cancer cells
BACKGROUND: Cell cycle regulation is a complex system consisting of growth-promoting and growth-restricting mechanisms, whose coordinated activity is vital for proper division and propagation. Alterations in this regulation may lead to uncontrolled proliferation and genomic instability, triggering c...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927170/ https://www.ncbi.nlm.nih.gov/pubmed/31889988 http://dx.doi.org/10.1186/s13008-019-0058-4 |