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Mechanisms for the temporal regulation of substrate ubiquitination by the anaphase-promoting complex/cyclosome
The anaphase-promoting complex/cyclosome (APC/C) is a multi-subunit, multifunctional ubiquitin ligase that controls the temporal degradation of numerous cell cycle regulatory proteins to direct the unidirectional cell cycle phases. Several different mechanisms contribute to ensure the correct order...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927175/ https://www.ncbi.nlm.nih.gov/pubmed/31889987 http://dx.doi.org/10.1186/s13008-019-0057-5 |