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Valproic Acid Addresses Neuroendocrine Differentiation of LNCaP Cells and Maintains Cell Survival

PURPOSE: Neuroendocrine differentiation of prostate cancer, induced by androgen deprivation therapy, is mainly related to advanced disease and poor clinical outcome. Genetic and epigenetic alterations are the key elements of the prostate carcinogenesis. A group of compounds able to induce changes in...

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Detalles Bibliográficos
Autores principales: Giordano, Francesca, Naimo, Giuseppina Daniela, Nigro, Alessandra, Romeo, Francesco, Paolì, Alessandro, De Amicis, Francesca, Vivacqua, Adele, Morelli, Catia, Mauro, Loredana, Panno, Maria Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927225/
https://www.ncbi.nlm.nih.gov/pubmed/31908413
http://dx.doi.org/10.2147/DDDT.S229930