Cargando…

Valproic Acid Addresses Neuroendocrine Differentiation of LNCaP Cells and Maintains Cell Survival

PURPOSE: Neuroendocrine differentiation of prostate cancer, induced by androgen deprivation therapy, is mainly related to advanced disease and poor clinical outcome. Genetic and epigenetic alterations are the key elements of the prostate carcinogenesis. A group of compounds able to induce changes in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Giordano, Francesca, Naimo, Giuseppina Daniela, Nigro, Alessandra, Romeo, Francesco, Paolì, Alessandro, De Amicis, Francesca, Vivacqua, Adele, Morelli, Catia, Mauro, Loredana, Panno, Maria Luisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927225/ https://www.ncbi.nlm.nih.gov/pubmed/31908413 http://dx.doi.org/10.2147/DDDT.S229930

Ejemplares similares

Poncirus trifoliata (L.) Raf. Seed Extract Induces Cell Cycle Arrest and Apoptosis in the Androgen Receptor Positive LNCaP Prostate Cancer Cells
por: Giordano, Francesca, et al.
Publicado: (2023)

Valproic acid inhibits cell growth in both MCF-7 and MDA-MB231 cells by triggering different responses in a cell type-specific manner
por: Giordano, Francesca, et al.
Publicado: (2023)

ADAMTS1 alters blood vessel morphology and TSP1 levels in LNCaP and LNCaP-19 prostate tumors
por: Gustavsson, Heléne, et al.
Publicado: (2010)

Unraveling the Role of Adiponectin Receptors in Obesity-Related Breast Cancer
por: Naimo, Giuseppina Daniela, et al.
Publicado: (2023)

The cannabinoid WIN 55,212-2 prevents neuroendocrine differentiation of LNCaP prostate cancer cells
por: Morell, C, et al.
Publicado: (2016)

Apogossypolone inhibits the proliferation of LNCaP cells in vitro and in vivo
por: ZHANG, XIANQING, et al.
Publicado: (2014)

Apogossypolone inhibits the proliferation of LNCaP cells in vitro and in vivo
por: Zhang, Xianqing, et al.
Publicado: (2018)

Autophagy Pathway Is Required for IL-6 Induced Neuroendocrine Differentiation and Chemoresistance of Prostate Cancer LNCaP Cells
por: Chang, Pei-Ching, et al.
Publicado: (2014)

Bergapten drives autophagy through the up-regulation of PTEN expression in breast cancer cells
por: De Amicis, Francesca, et al.
Publicado: (2015)

Up-Regulated Expression of LAMP2 and Autophagy Activity during Neuroendocrine Differentiation of Prostate Cancer LNCaP Cells
por: Morell, Cecilia, et al.
Publicado: (2016)

The deregulation of miR-17/CCND1 axis during neuroendocrine transdifferentiation of LNCaP prostate cancer cells
por: Dankert, Jaroslaw Thomas, et al.
Publicado: (2018)

Calcitriol and TO-901317 Interact in Human Prostate Cancer LNCaP Cells
por: Wang, Jing-Huan, et al.
Publicado: (2008)

Alteration of Androgen Receptor Protein Stability by Triptolide in LNCaP Cells
por: Li, Wei, et al.
Publicado: (2018)

URG11 promotes proliferation and induced apoptosis of LNCaP cells
por: Sun, Chenmin, et al.
Publicado: (2019)

Correlation Between PSMA and VEGF Expression as Markers for LNCaP Tumor Angiogenesis
por: Tsui, Paulus, et al.
Publicado: (2005)

Anti-Cancer Effect of Lambertianic Acid by Inhibiting the AR in LNCaP Cells
por: Lee, Myoung-Sun, et al.
Publicado: (2016)

Androgen-independent LNCaP cells are a subline of LNCaP cells with a more aggressive phenotype and androgen suppresses their growth by inducing cell cycle arrest at the G1 phase
por: Yu, Pan, et al.
Publicado: (2017)

Farnesoid X receptor inhibits LNcaP cell proliferation via the upregulation of PTEN
por: LIU, JUN, et al.
Publicado: (2014)

Androgen upregulates the palmitoylation of eIF3L in human prostate LNCaP cells
por: Cui, Luwei, et al.
Publicado: (2019)

Differentiation enhances aminolevulinic acid-dependent photodynamic treatment of LNCaP prostate cancer cells
por: Ortel, B, et al.
Publicado: (2002)

Synthetic androgens suppress the transformed phenotype in the human prostate carcinoma cell line LNCaP.
por: Wolf, D. A., et al.
Publicado: (1991)

LNCaP Atlas: Gene expression associated with in vivo progression to castration-recurrent prostate cancer
por: Romanuik, Tammy L, et al.
Publicado: (2010)

Phenotypic Characterization of Prostate Cancer LNCaP Cells Cultured within a Bioengineered Microenvironment
por: Sieh, Shirly, et al.
Publicado: (2012)

EphA2 enhances the proliferation and invasion ability of LNCaP prostate cancer cells
por: CHEN, PEIJIE, et al.
Publicado: (2014)

Effect of curcumin on the interaction between androgen receptor and Wnt/β-catenin in LNCaP xenografts
por: Hong, Jeong Hee, et al.
Publicado: (2015)

MiR‐145 affected the circular RNA expression in prostate cancer LNCaP cells
por: He, Jin‐Hua, et al.
Publicado: (2018)

Effect of CD133 overexpression on bone metastasis in prostate cancer cell line LNCaP
por: Sohn, Hong Moon, et al.
Publicado: (2019)

Chronic IL-1 exposure drives LNCaP cells to evolve androgen and AR independence
por: Dahl, Haley C., et al.
Publicado: (2020)

Enhanced Antitumor Efficacy of Radium-223 and Enzalutamide in the Intratibial LNCaP Prostate Cancer Model
por: Suominen, Mari I., et al.
Publicado: (2023)

Casodex treatment induces hypoxia-related gene expression in the LNCaP prostate cancer progression model
por: Rothermund, Christy A, et al.
Publicado: (2005)

Interleukin 1beta mediates the modulatory effects of monocytes on LNCaP human prostate cancer cells.
por: Culig, Z., et al.
Publicado: (1998)

Analysis of the prostate cancer cell line LNCaP transcriptome using a sequencing-by-synthesis approach
por: Bainbridge, Matthew N, et al.
Publicado: (2006)

Menthol Enhances an Antiproliferative Activity of 1α,25-Dihydroxyvitamin D(3) in LNCaP Cells
por: Park, Eun-Jung, et al.
Publicado: (2009)

Selenium enrichment of broccoli sprout extract increases chemosensitivity and apoptosis of LNCaP prostate cancer cells
por: Abdulah, Rizky, et al.
Publicado: (2009)

Correction: Phenotypic Characterization of Prostate Cancer LNCaP Cells Cultured within a Bioengineered Microenvironment
por: Sieh, Shirly, et al.
Publicado: (2013)

Role of Androgen Receptor in Progression of LNCaP Prostate Cancer Cells from G(1) to S Phase
por: Murthy, Shalini, et al.
Publicado: (2013)

Inhibition of IL-6 expression in LNCaP prostate cancer cells by a combination of atorvastatin and celecoxib
por: WANG, HUAQIAN, et al.
Publicado: (2014)

Role of EZH2 in the Growth of Prostate Cancer Stem Cells Isolated from LNCaP Cells
por: Li, Kuiqing, et al.
Publicado: (2013)

Synergistic Effects of NDRG2 Overexpression and Radiotherapy on Cell Death of Human Prostate LNCaP Cells
por: Alizadeh Zarei, M., et al.
Publicado: (2017)

MicroRNA-652 induces NED in LNCaP and EMT in PC3 prostate cancer cells
por: Nam, Robert K., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_gdjcd2vg9j4ikit3esv1d2hpl4