ADAM10 sheddase activation is controlled by cell membrane asymmetry

Dysregulation of the disintegrin-metalloproteinase ADAM10 may contribute to the development of diseases including tumorigenesis and Alzheimer’s disease. The mechanisms underlying ADAM10 sheddase activation are incompletely understood. Here, we show that transient exposure of the negatively charged p...

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Detalles Bibliográficos
Autores principales: Bleibaum, Florian, Sommer, Anselm, Veit, Martin, Rabe, Björn, Andrä, Jörg, Kunzelmann, Karl, Nehls, Christian, Correa, Wilmar, Gutsmann, Thomas, Grötzinger, Joachim, Bhakdi, Sucharit, Reiss, Karina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927242/
https://www.ncbi.nlm.nih.gov/pubmed/30753537
http://dx.doi.org/10.1093/jmcb/mjz008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927242/
https://www.ncbi.nlm.nih.gov/pubmed/30753537
http://dx.doi.org/10.1093/jmcb/mjz008

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