Citron kinase interacts with LATS2 and inhibits its activity by occluding its hydrophobic phosphorylation motif

The inhibitory effect of large tumor suppressor kinase (LATS1/2) on the activity of the oncoprotein yes-associated protein (YAP) is crucial to maintain tissue homeostasis. Proteomic studies have identified several new regulators of this process. Recently, citron kinase (CIT) was listed as a potentia...

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Detalles Bibliográficos
Autores principales: Tran, Thi Hai Yen, Yang, Dae-Wook, Kim, Minchul, Lee, Da-Hye, Gai, Marta, Di Cunto, Ferdinando, Choi, Kwang-Wook, Lim, Dae-Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927243/
https://www.ncbi.nlm.nih.gov/pubmed/30865227
http://dx.doi.org/10.1093/jmcb/mjz013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927243/
https://www.ncbi.nlm.nih.gov/pubmed/30865227
http://dx.doi.org/10.1093/jmcb/mjz013

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