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Citron kinase interacts with LATS2 and inhibits its activity by occluding its hydrophobic phosphorylation motif
The inhibitory effect of large tumor suppressor kinase (LATS1/2) on the activity of the oncoprotein yes-associated protein (YAP) is crucial to maintain tissue homeostasis. Proteomic studies have identified several new regulators of this process. Recently, citron kinase (CIT) was listed as a potentia...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927243/ https://www.ncbi.nlm.nih.gov/pubmed/30865227 http://dx.doi.org/10.1093/jmcb/mjz013 |