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Wnt Signaling and Its Significance Within the Tumor Microenvironment: Novel Therapeutic Insights

Wnt signaling is one of the central mechanisms regulating tissue morphogenesis during embryogenesis and repair. The pivot of this signaling cascade is the Wnt ligand, which binds to receptors belonging to the Frizzled family or the ROR1/ROR2 and RYK family. This interaction governs the downstream si...

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Detalles Bibliográficos
Autores principales: Patel, Sonal, Alam, Aftab, Pant, Richa, Chattopadhyay, Samit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927425/
https://www.ncbi.nlm.nih.gov/pubmed/31921137
http://dx.doi.org/10.3389/fimmu.2019.02872