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Wnt Signaling and Its Significance Within the Tumor Microenvironment: Novel Therapeutic Insights
Wnt signaling is one of the central mechanisms regulating tissue morphogenesis during embryogenesis and repair. The pivot of this signaling cascade is the Wnt ligand, which binds to receptors belonging to the Frizzled family or the ROR1/ROR2 and RYK family. This interaction governs the downstream si...
Autores principales: | Patel, Sonal, Alam, Aftab, Pant, Richa, Chattopadhyay, Samit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927425/ https://www.ncbi.nlm.nih.gov/pubmed/31921137 http://dx.doi.org/10.3389/fimmu.2019.02872 |
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