The Ciliary Protein Arl13b Functions Outside of the Primary Cilium in Shh-Mediated Axon Guidance

The small GTPase Arl13b is enriched in primary cilia and regulates Sonic hedgehog (Shh) signaling. During neural development, Shh controls patterning and proliferation through a canonical, transcription-dependent pathway that requires the primary cilium. Additionally, Shh controls axon guidance thro...

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Detalles Bibliográficos
Autores principales: Ferent, Julien, Constable, Sandii, Gigante, Eduardo D., Yam, Patricia T., Mariani, Laura E., Legué, Emilie, Liem, Karel F., Caspary, Tamara, Charron, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927553/
https://www.ncbi.nlm.nih.gov/pubmed/31825820
http://dx.doi.org/10.1016/j.celrep.2019.11.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927553/
https://www.ncbi.nlm.nih.gov/pubmed/31825820
http://dx.doi.org/10.1016/j.celrep.2019.11.015

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